In conclusion, EDA biofeedback has great potential as a non-pharmacological therapy for the management of refractory epilepsy. The methodology is grounded on theory, and on increasing knowledge regarding the underlying neural mechanisms, and the approach deserves greater clinical attention. There also remains a need for continuing clinical research, such as the case study report by Scrimali et al. (2015). Despite some inaccurate interpretations of findings of published EDA biofeedback papers, the study of Scrimali et al. rises the need to develop noninvasive biobehavioral treatment that target specifically pré-ictal/ictal periods or interical periods to manage efficiently patients with refractory epilepsy.
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