http://www.nature.com/nrn/journal/v11/n ... n2782.html
Neurological disorders: Inhibition: too much of a good thing?
Katherine Whalley
Abstract
Absence seizures, characterized by a spike and wave discharge (SWD) pattern in thalamocortical networks, occur in many types of epilepsy. The cellular mechanisms underlying these seizures are unclear; however, a new paper by Cope et al. reveals that enhanced neuronal inhibition causes seizures in several animal models of absence epilepsy.
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